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A comparative account of microRNA resources, feature-validations and application-based categorizations

miRGator, miRGator v2.0

Tool namemiRGator, miRGator v2.0
URL1. http://genome.ewha.ac.kr/miRGator/ 2. http://miRGator.kobic.re.kr
Important features An integrated database for functional annotation of microRNA that includes expression, regulation, function, pathway,pathological or disease terms as well as microRNA targeting (miRanda, picTar and TargetScan).
Citations Nam S, Kim B, Shin S, Lee S. miRGator: an integrated system for functional annotation of microRNAs. Nucleic Acids Res. 2008 Jan;36(Database issue):D159-64. Epub 2007 Oct 16. PubMed PMID: 17942429
Year of publication2008
Rank by usage frequency100
Comments
FunctionFIND TARGET: integrated tools, DISEASE/ TISSUE SPECIFIC, SPECIES: mouse, 1. http://genome.ewha.ac.kr/miRGator/ 2. http://miRGator.kobic.re.kr 3. http://mirgator.kobic.re.kr:8080/MEXWebApp/, An integrated database for functional annotation of microRNA that includes expression- regulation- function- pathway-pathological or disease terms as well as microRNA targeting (miRanda- picTar and TargetScan). , Nam S- Kim B- Shin S- Lee S. miRGator: an integrated system for functional annotation of microRNAs. Nucleic Acids Res. 2008 Jan;36(Database issue):D159-64. Epub 2007 Oct 16. PubMed PMID: 17942429, 2008, 100, Online, I. SPECIES SUPPORTED INCLUDE: human- mouse II. QUERY OR INPUT DATA: 1. Dataset analysis: miRNA- Target gene (Gene symbol or alias or Entrez gene id)- Tissue- Disease- Perturbation. 2. Association analysis: 1. miRNA Set Analysis-select disease-miRNAs or DEmiRs(Up or down regulated- Input filter-tissue- disease- perturbation 2. Gene Set Analysis-anti-coexpressed genes with miRNA or mirna perturbed DEGs- or predicted miRNA targets 3. miRNA profile analysis- miRNA expression profile or miRNA phenotype profile 3. miRNA set analysis and Gene set analysis- Add mirna set or gene set III. OUTPUT DATA: depending on the type of analysis chosen the results are related to microRNA expressional profile- gene expression profile under altered microRNA states- details of validated and predicted microRNA targets and microRNA disease associations., Cho S- Jun Y- Lee S- Choi HS- Jung S- Jang Y- Park C- Kim S- Lee S- Kim W. miRGator v2.0: an integrated system for functional investigation of microRNAs. Nucleic Acids Res. 2011 Jan;39(Database issue):D158-62. Epub 2010 Nov 9. PubMed PMID: 21062822.
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